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Scientific publications

genOway has been acknowledged in the following articles for the generation of the mouse/rat models
Hofmann LP, Ren S, Schwalm S, Pfeilschifter J, Huwiler A.
Sphingosine kinase 1 and 2 regulate the capacity of mesangial cells to resist apoptotic stimuli in an opposing manner.
Biol Chem. 2008 Nov;389(11):1399-407.
Lastres-Becker I, Brodesser S, Lütjohann D, Azizov M, Buchmann J, Hintermann E, Sandhoff K, Schürmann A, Nowock J, Auburger G.
Insulin receptor and lipid metabolism pathology in ataxin-2 knock-out mice.
Hum Mol Genet. 2008 Feb 13
Ferry G, Giganti A, Coge F, Bertaux F, Thiam K, Boutin JA.
Functional invalidation of the autotaxin gene by a single amino acid mutation in mouse is lethal.
FEBS Lett. 2007 Jul 24;581(18):3572-8
Smart N, Risebro CA, Melville AA, Moses K, Schwartz RJ, Chien KR, Riley PR.
Thymosin beta4 induces adult epicardial progenitor mobilization and neovascularization.
Nature. 2007 Jan 11;445(7124):177-82.
Klawitter S, Hofmann LP, Pfeilschifter J, Huwiler A.
Extracellular nucleotides induce migration of renal mesangial cells by upregulating sphingosine kinase-1 expression and activity.
Br J Pharmacol. 2007 Feb;150(3):271-80. Epub 2007 Jan 2.
Chambrey R, Goossens D, Bourgeois S, Picard N, Bloch-Faure M, Leviel F, Geoffroy V, Cambillau M, Colin Y, Paillard M, Houillier P, Cartron JP, Eladari D
Genetic ablation of Rhbg in the mouse does not impair renal ammonium excretion.
Am J Physiol Renal Physiol. 2005 Dec;289(6):F1281-90.
Mailliet F, Ferry G, Vella F, Thiam K, Delagrange P, Boutin JA.
Organs from mice deleted for NRH:quinone oxidoreductase 2 are deprived of the melatonin binding site MT3.
FEBS Lett. 2004 Dec 3;578(1-2):116-20.
Chevillard G, Clemencet MC, Latruffe N, Nicolas-Frances V.
Targeted disruption of the peroxisomal thiolase B gene in mouse: a new model to study disorders related to peroxisomal lipid metabolism.
Biochimie. 2004 Nov;86(11):849-56.
Roselli S, Heidet L, Sich M, Henger A, Kretzler M, Gubler MC, Antignac C.
Early glomerular filtration defect and severe renal disease in podocin-deficient mice.
Mol Cell Biol. 2004 Jan;24(2):546-60.
Merlo GR, Paleari L, Mantero S, Genova F, Beverdam A, Palmisano GL, Barbieri O, Levi G.
Mouse model of split hand/foot malformation type I.
Genesis. 2002 Jun;33(2):97-101.
genOway is the author of the following publications:
Cozzi J, Fraichard A, Thiam K.
Use of genetically modified rat models for translational medicine.
Drug Discov Today 2008; 13: 488-494.
Tesson L, Cozzi J, Menoret S, Remy S, Usal C, Fraichard A, Anegon I.
Transgenic modifications of the rat genome.
Transgenic Res. 2005 Oct;14(5):531-46.
Zhou Q, Renard JP, Le Friec G, Brochard V, Beaujean N, Cherifi Y, Fraichard A, Cozzi J.
Generation of fertile cloned rats by regulating oocyte activation.
Science. 2003 Nov 14;302(5648):1179. Epub 2003 Sep 25.
Article in Book:

"Procedures for somatic cell nuclear transfer in the rat" Jean Cozzi, Eryao Wang, Christelle Jacquet, Alexandre Fraichard, Yacine Cherifi, Qi Zhou. Methods and Protocols, Methods in Molecular Biology, vol 597, Humana Press 2010

"Interference RNA for in vivo knock-down of gene expression or genome-wide screening using shRNA". Petit S, Thiam K. In: Anegon (ed.). Rat genomics: Methods and Protocols, Methods in Molecular Biology, vol 597, @ Humana Press 2010

"Pronuclear DNA injection for the production of transgenic rats". Cozzi J, Fraichard A, Braun V, Gross A-C, Merrouche C, Anegon I, Thiam K. In: Transgenesis, Third Edition. (in press); 2008

"in vivo RNA interference: another tool in the Box?" in Non-viral Gene Therapy - Gene design and Delivery. Taira, K.; Kataoka, K.; Niidome, T. (Eds.) @ Springer-verlag Tokyo 2005
Transgenics (rat and mouse gene modification): knockout mouse (KO mouse), knock in mice (KI mice) and transgenic mouse
genOway, service provider in transgenesis for customized genetically modified mice and rats: gene overexpression, gene knockdown, gene knockout, etc.
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