Publications 2009/10

genOway - Client publication 2009-10

genOway has been acknowledged in numerous articles for the generation of mouse, rat, and cell line models.

Here, a selection of these publications:

Abdul-Sater AA, Saïd-Sadier N, Lam VM, Singh B, Pettengill MA, Soares F, Tattoli I, Lipinski S, Girardin SE, Rosenstiel P, Ojcius DM.
Enhancement of reactive oxygen species production and chlamydial infection by the mitochondrial Nod-like family member NLRX1.
J Biol Chem. 2010 Dec 31;285(53):41637-45.

Jawhar S, Wirths O, Schilling S, Graubner S, Demuth HU, Bayer TA.
Overexpression of glutaminyl cyclase, the enzyme responsible for pyroglutamate abeta formation, induces behavioral deficits and glutaminyl cyclase knock-out rescues the behavioral phenotype in 5XFAD mice.
J Biol Chem. 2010 Dec 10.

Holland S, Coste O, Zhang DD, Pierre SC, Geisslinger G, Scholich K.
The ubiquitin ligase MYCBP2 regulates transient receptor potential vanilloid receptor 1 (TRPV1)-internalization through inhibition of p38 MAPK signaling.
J Biol Chem. 2010 Nov 23.

Al-Mutairi MS, Cadalbert LC, McGachy HA, Shweash M, Schroeder J, Kurnik M, Sloss CM, Bryant CE, Alexander J, Plevin R.
MAP kinase phosphatase-2 plays a critical role in response to infection by Leishmania mexicana.
PLoS Pathog. 2010 Nov 11;6(11):e1001192.

Thomas DM, Angoa Pérez M, Francescutti-Verbeem DM, Shah MM, Kuhn DM.
The role of endogenous serotonin in methamphetamine-induced neurotoxicity to dopamine nerve endings of the striatum.
J Neurochem. 2010 Nov.

Zhang M, Brewer AC, Schröder K, Santos CX, Grieve DJ, Wang M, Anilkumar N, Yu B, Dong X, Walker SJ, Brandes RP, Shah AM.
NADPH oxidase-4 mediates protection against chronic load-induced stress in mouse hearts by enhancing angiogenesis.
Proc Natl Acad Sci U S A. 2010 Oct 19;107(42):18121-6.

Magill CK, Moore AM, Borschel GH, Mackinnon SE.
A new model for facial nerve research: the novel transgenic Thy1-GFP rat.
Arch Facial Plast Surg. 2010 Sep-Oct;12(5):315-20.

Lamacchia C, Palmer G, Bischoff L, Rodriguez E, Talabot-Ayer D, Gabay C.
Distinct roles of hepatocyte- and myeloid cell-derived IL-1 receptor antagonist during endotoxemia and sterile inflammation in mice.
J Immunol. 2010 Aug 15;185(4):2516-24

Martinez P, Thanasoula M, Carlos AR, Gómez-López G, Tejera AM, Schoeftner S, Dominguez O, Pisano DG, Tarsounas M, Blasco MA.
Mammalian Rap1 controls telomere function and gene expression through binding to telomeric and extratelomeric sites.
Nat Cell Biol. 2010 Aug;12(8):768-80

Wijesekara N, Dai FF, Hardy AB, Giglou PR, Bhattacharjee A, Koshkin V, Chimienti F, Gaisano HY, Rutter GA, Wheeler MB.
Beta cell-specific Znt8 deletion in mice causes marked defects in insulin processing, crystallisation and secretion.
Diabetologia. 2010 Aug;53(8):1656-68.

Ledonne A, Federici M, Giustizieri M, Pessia M, Imbrici P, Millan MJ, Bernardi G, Mercuri NB.
Trace amines depress D(2)-autoreceptor-mediated responses on midbrain dopaminergic cells.
Br J Pharmacol. 2010 Jul;160(6):1509-20. doi: 10.1111/j.1476-5381.2010.00792.x.

Sven Müller-Loennies 1, Giovanna Galliciotti, Katrin Kollmann, Markus Glatzel, Thomas Braulke.
A novel single-chain antibody fragment for detection of mannose 6-phosphate-containing proteins: application in mucolipidosis type II patients and mice.
Am J Pathol. 2010 Jul

Sun G, Tarasov AI, McGinty J, McDonald A, da Silva Xavier G, Gorman T, Marley A, French PM, Parker H, Gribble F, Reimann F, Prendiville O, Carzaniga R, Viollet B, Leclerc I, Rutter GA.
Ablation of AMP-activated protein kinase alpha1 and alpha2 from mouse pancreatic beta cells and RIP2.Cre neurons suppresses insulin release in vivo.
Diabetologia. 2010 May;53(5):924-36. Epub 2010 Mar 11.

Saharinen P, Helotera H, Miettinen J, Norrmen C, D'Amico G, Jeltsch M, Langenberg T, Vandevelde W, Ny A, Dewerchin M, Carmeliet P, Alitalo K.
Claudin-like protein 24 interacts with the VEGFR-2 and VEGFR-3 pathways and regulates lymphatic vessel development.
Genes Dev. 2010 May;24(9):875-80.

Songe-Møller L, van den Born E, Leihne V, Vågbø CB, Kristoffersen T, Krokan HE, Kirpekar F, Falnes PØ, Klungland A.
Mammalian ALKBH8 possesses tRNA methyltransferase activity required for the biogenesis of multiple wobble uridine modifications implicated in translational decoding.
Mol Cell Biol. 2010 Apr;30(7):1814-27.

Lamacchia C, Palmer G, Seemayer CA, Talabot-Ayer D, Gabay C.
Enhanced Th1 and Th17 responses and arthritis severity in mice with a deficiency of myeloidcell-specific interleukin-1 receptor antagonist.
Arthritis Rheum. 2010 Feb;62(2):452-62

D'Amico G, Korhonen EA, Waltari M, Saharinen P, Laakkonen P, Alitalo K.
Loss of endothelial Tie1 receptor impairs lymphatic vessel development-brief report.
Arterioscler Thromb Vasc Biol. 2010 Feb;30(2):207-9.

Bujakowska K, Maubaret C, Chakarova CF, Tanimoto N, Beck SC, Fahl E, Humphries MM, Kenna PF, Makarov E, Makarova O, Paquet-Durand F, Ekström PA, van Veen T, Leveillard T, Humphries P, Seeliger MW, Bhattacharya SS.
Study of gene-targeted mouse models of splicing factor gene Prpf31 implicated in human autosomal dominant retinitis pigmentosa (RP).
Invest Ophthalmol Vis Sci. 2009 Dec;50(12):5927-33.

Steinmetz OM, Turner JE, Paust HJ, Lindner M, Peters A, Heiss K, Velden J, Hopfer H, Fehr S, Krieger T, Meyer-Schwesinger C, Meyer TN, Helmchen U, Mittrücker HW, Stahl RA, Panzer U.
CXCR3 mediates renal Th1 and Th17 immune response in murine lupus nephritis.
J Immunol. 2009 Oct 1;183(7):4693-704.

Arnauld S, Fidaleo M, Clémencet MC, Chevillard G, Athias A, Gresti J, Wanders RJ, Latruffe N, Nicolas-Francès V, Mandard S.
Modulation of the hepatic fatty acid pool in peroxisomal 3-ketoacyl-CoA thiolase B-null mice exposed to the selective PPARalpha agonist Wy14,643.
Biochimie. 2009 Nov-Dec.

Favaro R, Valotta M, Ferri AL, Latorre E, Mariani J, Giachino C, Lancini C, Tosetti V, Ottolenghi S, Taylor V, Nicolis SK.
Hippocampal development and neural stem cell maintenance require Sox2-dependent regulation of Shh.
Nat Neurosci. 2009 Oct;12(10):1248-56. doi: 10.1038/nn.2397. Epub 2009 Sep 6.

Wirths O, Breyhan H, Cynis H, Schilling S, Demuth HU, Bayer TA.
Intraneuronal pyroglutamate-Abeta 3-42 triggers neurodegeneration and lethal neurological deficits in a transgenic mouse model.
Acta Neuropathol. 2009 Oct;118(4):487-96.

David V, Martin A, Hedge AM, Rowe PS.
Matrix extracellular phosphoglycoprotein (MEPE) is a new bone renal hormone and vascularization modulator.
Endocrinology. 2009 Sep;150(9):4012-23.

Lemaire K, Ravier MA, Schraenen A, Creemers JW, Van de Plas R, Granvik M, Van Lommel L, Waelkens E, Chimienti F, Rutter GA, Gilon P, in't Veld PA, Schuit FC.
Insulin crystallization depends on zinc transporter ZnT8 expression, but is not required for normal glucose homeostasis in mice.
Proc Natl Acad Sci U S A. 2009 Sep 1;106(35):14872-7.

Nicolson TJ, Bellomo EA, Wijesekara N, Loder MK, Baldwin JM, Gyulkhandanyan AV, Koshkin V, Tarasov AI, Carzaniga R, Kronenberger K, Taneja TK, da Silva Xavier G, Libert S, Froguel P, Scharfmann R, Stetsyuk V, Ravassard P, Parker H, Gribble FM, Reimann F, Sladek R, Hughes SJ, Johnson PR, Masseboeuf M, Burcelin R, Baldwin SA, Liu M, Lara-Lemus R, Arvan P, Schuit FC, Wheeler MB, Chimienti F, Rutter GA.
Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants.
Diabetes. 2009 Sep;58(9):2070-83.

Johswich K, Martin M, Bleich A, Kracht M, Dittrich-Breiholz O, Gessner JE, Suerbaum S, Wende E, Rheinheimer C, Klos A.
Role of the C5a receptor (C5aR) in acute and chronic dextran sulfate-induced models of inflammatory bowel disease.
Inflamm Bowel Dis. 2009 Aug 27;15(12):1812-1823.

Chistiakov DA, Voronova NV.
Zn(2+)-transporter-8: a dual role in diabetes.
Biofactors. 2009 Jul-Aug;35(4):356-63.

Pushparaj PN, Manikandan J, Tay HK, H'ng SC, Kumar SD, Pfeilschifter J, Huwiler A, Melendez AJ.
Sphingosine kinase 1 is pivotal for Fc epsilon RI-mediated mast cell signaling and functional responses in vitro and in vivo.
J Immunol. 2009 Jul 1;183(1):221-7.

Linder AE, Beggs KM, Burnett RJ, Watts SW.
Body distribution of infused serotonin in rats.
Clin Exp Pharmacol Physiol. 2009 May;36(5-6):599-601. doi: 10.1111/j.1440-1681.2009.05147.x. Epub 2009 Jan 18.

Dobbertin A, Hrabovska A, Dembele K, Camp S, Taylor P, Krejci E, Bernard V.
Targeting of acetylcholinesterase in neurons in vivo: a dual processing function for the proline-rich membrane anchor subunit and the attachment domain on the catalytic subunit.
J Neurosci. 2009 Apr 8;29(14):4519-30.

Guyon A, Tardy MP, Rovère C, Nahon JL, Barhanin J, Lesage F.
Glucose inhibition persists in hypothalamic neurons lacking tandem-pore K+ channels.
J Neurosci. 2009 Feb 25;29(8):2528-33.


genOway is the author of the following publications:

Satoh-Takayama N, Vosshenrich CA, Lesjean-Pottier S, Sawa S, Lochner M, Rattis F, Mention JJ, Thiam K, Cerf-Bensussan N, Mandelboim O, Eberl G, Di Santo JP.
Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense.
Immunity. 2008 Dec 19;29(6):958-70. doi: 10.1016/j.immuni.2008.11.001. Epub 2008 Dec 11.

Cozzi J, Fraichard A, Thiam K.
Use of genetically modified rat models for translational medicine.
Drug Discov Today 2008; 13: 488-494.

Tesson L, Cozzi J, Menoret S, Remy S, Usal C, Fraichard A, Anegon I.
Transgenic modifications of the rat genome.
Transgenic Res. 2005 Oct;14(5):531-46.

Zhou Q, Renard JP, Le Friec G, Brochard V, Beaujean N, Cherifi Y, Fraichard A, Cozzi J.
Generation of fertile cloned rats by regulating oocyte activation.
Science. 2003 Nov 14;302(5648):1179. Epub 2003 Sep 25.

Article in Book:

"Procedures for somatic cell nuclear transfer in the rat" Jean Cozzi, Eryao Wang, Christelle Jacquet, Alexandre Fraichard, Yacine Cherifi, Qi Zhou. Methods and Protocols, Methods in Molecular Biology, vol 597, Humana Press 2010

"Interference RNA for in vivo knock-down of gene expression or genome-wide screening using shRNA". Petit S, Thiam K. In: Anegon (ed.). Rat genomics: Methods and Protocols, Methods in Molecular Biology, vol 597, @ Humana Press 2010

"Pronuclear DNA injection for the production of transgenic rats". Cozzi J, Fraichard A, Braun V, Gross A-C, Merrouche C, Anegon I, Thiam K. In: Transgenesis, Third Edition. 2008

"in vivo RNA interference: another tool in the Box?" in Non-viral Gene Therapy - Gene design and Delivery. Taira, K.; Kataoka, K.; Niidome, T. (Eds.) @ Springer-verlag Tokyo 2005