Publications 2013/14

genOway - Client publication 2013-14

genOway has been acknowledged in numerous articles for the generation of mouse, rat, and cell line models.

Here, a selection of these publications:

Weston CJ, Shepherd EL, Claridge LC, Rantakari P, Curbishley SM, Tomlinson JW, Hubscher SG, Reynolds GM, Aalto K, Anstee QM, Jalkanen S, Salmi M, Smith DJ, Day CP, Adams DH
Vascular adhesion protein-1 promotes liver inflammation and drives hepatic fibrosis.
J Clin Invest. 2014 Dec 22.

Thorens B, Tarussio D, Maestro MA, Rovira M, Heikkilä E, Ferrer J
Ins1 Cre knock-in mice for beta cell-specific gene recombination.
Diabetologia. 2014 Dec 11.

Chen X, Baumlin N, Buck J, Levin LR, Fregien N, Salathe M
A soluble adenylyl cyclase form targets to axonemes and rescues beat regulation in soluble adenylyl cyclase knockout mice.
Am J Respir Cell Mol Biol. 2014 Dec.

Mandal P, Berger SB, Pillay S, Moriwaki K, Huang C, Guo H, Lich JD, Finger J, Kasparcova V, Votta B, Ouellette M, King BW, Wisnoski D, Lakdawala AS, DeMartino MP, Casillas LN, Haile PA, Sehon CA, Marquis RW, Upton J, Daley-Bauer LP, Roback L, Ramia N, Dovey CM, Carette JE, Chan FK, Bertin J, Gough PJ, Mocarski ES, Kaiser WJ.
RIP3 induces apoptosis independent of pronecrotic kinase activity.
Mol Cell. 2014 Nov 20.

Clemen CS, Stöckigt F, Strucksberg KH, Chevessier F, Winter L, Schütz J, Bauer R, Thorweihe JM, Wenzel D, Schlötzer-Schrehardt U, Rasche V, Krsmanovic P, Katus HA, Rottbauer W, Just S, Müller OJ, Friedrich O, Meyer R, Herrmann H, Schrickel JW, Schröder R
The toxic effect of R350P mutant desmin in striated muscle of man and mouse.
Acta Neuropathol. 2014 Nov 14.

Shih DQ, Zheng L, Zhang X, Zhang H, Kanazawa Y, Ichikawa R, Wallace KL, Chen J, Pothoulakis C, Koon HW, Targan SR
Inhibition of a novel fibrogenic factor Tl1a reverses established colonic fibrosis.
Mucosal Immunol. 2014 Nov.

Pagliarani S, Lucchiari S, Ulzi G, Violano R, Ripolone M, Bordoni A, Nizzardo M, Gatti S, Corti S, Moggio M, Bresolin N, Comi GP
Glycogen storage disease type III: A novel Agl knockout mouse model.
Biochim Biophys Acta. 2014 Nov.

Ilmjärv S, Reimets R, Hundahl CA, Luuk H
Effect of light on global gene expression in the neuroglobin-deficient mouse retina.
Biomed Rep. 2014 Nov.

Angoa-Pérez M, Kane MJ, Briggs DI, Herrera-Mundo N, Sykes CE, Francescutti DM, Kuhn DM.
Mice genetically depleted of brain serotonin do not display a depression-like behavioral phenotype.
ACS Chem Neurosci. 2014 Oct 15.

Iqbal AJ, McNeill E, Kapellos TS, Regan-Komito D, Norman S, Burd S, Smart N, Machemer DE, Stylianou E, McShane H, Channon KM, Chawla A, Greaves DR
Human CD68 promoter GFP transgenic mice allow analysis of monocyte to macrophage differentiation in vivo.
Blood. 2014 Oct 9.

Smith ML, Oliveira Souza FG, Bruce KS, Strang CE, Morley BJ, Keyser KT
Acetylcholine receptors in the retinas of the α7 nicotinic acetylcholine receptor knockout mouse
Molecular Vision. 2014 Sep 20.

Moyes AJ, Khambata RS, Villar I, Bubb KJ, Baliga RS, Lumsden NG, Xiao F, Gane PJ, Rebstock AS, Worthington RJ, Simone MI, Mota F, Rivilla F, Vallejo S, Peiró C, Sánchez Ferrer CF, Djordjevic S, Caulfield MJ, MacAllister RJ, Selwood DL, Ahluwalia A, Hobbs AJ
Endothelial C-type natriuretic peptide maintains vascular homeostasis.
J Clin Invest. 2014 Sep 2.

Daniel JM, Penzkofer D, Teske R, Dutzmann J, Koch A, Bielenberg W, Bonauer A, Boon RA, Fischer A, Bauersachs J, van Rooij E, Dimmeler S, Sedding DG.
Inhibition of miR-92a improves re-endothelialization and prevents neointima formation following vascular injury.
Cardiovasc Res. 2014 Sep 1.

Angoa-Pérez M, Kane MJ, Sykes CE, Perrine SA, Church MW, Kuhn DM.
Brain serotonin determines maternal behavior and offspring survival.
Genes Brain Behav. 2014 Sep.

Rosendahl A, Niemann G, Lange S, Ahadzadeh E, Krebs C, Contrepas A, van Goor H, Wiech T, Bader M, Schwake M, Peters J, Stahl R, Nguyen G, Wenzel UO
Increased expression of (pro)renin receptor does not cause hypertension or cardiac and renal fibrosis in mice.
Lab Invest. 2014 Aug.

Dodd GT, Worth AA, Nunn N, Korpal AK, Bechtold DA, Allison MB, Myers MG Jr, Statnick MA, Luckman SM
The Thermogenic Effect of Leptin Is Dependent on a Distinct Population of Prolactin-Releasing Peptide Neurons in the Dorsomedial Hypothalamus.
Cell Metab. 2014 Aug 27.

Nilsen A, Fusser M, Greggains G, Fedorcsak P, Klungland A
ALKBH4 Depletion in Mice Leads to Spermatogenic Defects.
PLoS One. 2014 Aug 25.

Plucińska K, Crouch B, Koss D, Robinson L, Siebrecht M, Riedel G, Platt B
Knock-in of human BACE1 cleaves murine APP and reiterates Alzheimer-like phenotypes.
J Neurosci. 2014 Aug 6.

McNeill E, Iqbal AJ, Patel J, White GE, Regan-Komito D, Greaves DR, Channon KM
Contrasting in vitro vs. in vivo effects of a cell membrane-specific CC-chemokine binding protein on macrophage chemotaxis.
J Mol Med (Berl). 2014 Aug 1.

Shih PY, Engle SE, Oh G, Deshpande P, Puskar NL, Lester HA, Drenan RM
Differential expression and function of nicotinic acetylcholine receptors in subdivisions of medial habenula.
J Neurosci. 2014 Jul 16.

Sun Y, Caplazi P, Zhang J, Mazloom A, Kummerfeld S, Quinones G, Senger K, Lesch J, Peng I, Sebrell A, Luk W, Lu Y, Lin Z, Barck K, Young J, Del Rio M, Lehar S9, Asghari V8, Lin W1, Mariathasan S9, DeVoss J1, Misaghi S10, Balazs M1, Sai T5, Haley B, Hass PE, Xu M, Ouyang W, Martin F, Lee WP, Zarrin AA
PILRα negatively regulates mouse inflammatory arthritis.
J Immunol. 2014 Jul 15.

Foronda M, Martínez P, Schoeftner S, Gómez-López G, Schneider R, Flores JM, Pisano DG, Blasco MA
Sox4 Links Tumor Suppression to Accelerated Aging in Mice by Modulating Stem Cell Activation.
Cell Rep. 2014 Jul 15.

Tordoff MG, Ellis HT, Aleman TR, Downing A, Marambaud P, Foskett JK, Dana RM, McCaughey SA
Salty Taste Deficits in CALHM1 Knockout Mice.
Chem Senses. 2014 Jul.

Penzkofer D, Bonauer A, Fischer A, Tups A, Brandes RP, Zeiher AM, Dimmeler S
Phenotypic Characterization of miR-92a-/- Mice Reveals an Important Function of miR-92a in Skeletal Development.
PLoS One. 2014 Jun 30.

Lizarraga LE, Phan AV, Cholanians AB, Herndon JM, Lau SS, Monks TJ
Serotonin reuptake transporter deficiency modulates the acute thermoregulatory and locomotor activity response to 3,4-(±)-methylenedioxymethamphetamine, and attenuates depletions in serotonin levels in SERT-KO rats.
Toxicol Sci. 2014 Jun.

Berger SB, Kasparcova V, Hoffman S, Swift B, Dare L, Schaeffer M, Capriotti C, Cook M, Finger J, Hughes-Earle A, Harris PA, Kaiser WJ, Mocarski ES, Bertin J, Gough PJ
RIP1 kinase activity is dispensable for normal development but is a key regulator of inflammation in SHARPIN-deficient mice.
J Immunol. 2014 Jun 15.

Thomas PS, Rajderkar S, Lane J, Mishina Y, Kaartinen V
AcvR1-mediated BMP signaling in second heart field is required for arterial pole development: Implications for myocardial differentiation and regional identity.
Dev Biol. 2014 Jun 15.

Fahs SA, Hille MT, Shi Q, Weiler H, Montgomery RR
A conditional knockout mouse model reveals endothelial cells as the principal and possibly exclusive source of plasma factor VIII.
Blood. 2014 Jun 12.

Parra S, Huang X, Charbeneau RA, Wade SM, Kaur K, Rorabaugh BR, Neubig RR
Conditional disruption of interactions between Gαi2 and regulator of G protein signaling (RGS) proteins protects the heart from ischemic injury.
BMC Pharmacol Toxicol. 2014 Jun 5.

Dioszeghy V, Mondoulet L, Dhelft V, Ligouis M, Puteaux E, Dupont C, Benhamou PH
The regulatory T cells induction by Epicutaneous immunotherapy is sustained and mediates long term protection from eosinophilic disorders in peanut sensitized mice.
Clin Exp Allergy. 2014 Mar 25.

Newton K, Dugger DL, Wickliffe KE, Kapoor N, de Almagro MC, Vucic D, Komuves L, Ferrando RE, French DM, Webster J, Roose-Girma M, Warming S, Dixit VM
Activity of protein kinase RIPK3 determines whether cells die by necroptosis or apoptosis.
Science. 2014 Mar 21.

Borroto A, Arellano I, Blanco R, Fuentes M, Orfao A, Dopfer EP, Prouza M, Suchànek M, Schamel WW, Alarcón B
Relevance of Nck-CD3 epsilon interaction for T cell activation in vivo.
J Immunol. 2014 Mar 1.

LeBlanc AC, Ramcharitar J, Afonso V, Hamel E, Bennett DA, Pakavathkumar P, Albrecht S
Caspase-6 activity in the CA1 region of the hippocampus induces age-dependent memory impairment.
Cell Death Differ. 2014 May 21.

Núñez B, Martínez de Mena R, Obregon MJ, Font-Llitjós M, Nunes V, Palacín M, Dumitrescu AM, Morte B, Bernal J
Cerebral cortex hyperthyroidism of newborn mct8-deficient mice transiently suppressed by lat2 inactivation.
PLoS One. 2014 May 12.

Li LC, Wang Y, Carr R, Haddad CS, Li Z, Qian L, Oberholzer J, Maker AV, Wang Q, Prabhakar BS
IG20/MADD Plays a Critical Role in Glucose-Induced Insulin Secretion.
Diabetes. 2014 May.

Polato F, Rusconi P, Zangrossi S, Morelli F, Boeri M, Musi A, Marchini S, Castiglioni V, Scanziani E, Torri V, Broggini M
DRAGO (KIAA0247), a New DNA Damage-Responsive, p53-Inducible Gene That Cooperates With p53 as Oncosupprossor.
J Natl Cancer Inst. 2014 Apr.

Clarke SE, Kang JX, Ma DW
The iFat1 transgene permits conditional endogenous n-3 PUFA enrichment both in vitro and in vivo.
Transgenic Res. 2014 Mar 13.

Nicolas-Francès V, Arnauld S, Kaminski J, Ver Loren van Themaat E, Clémencet MC, Chamouton J, Athias A, Grober J, Gresti J, Degrace P, Lagrost L, Latruffe N, Mandard S
Disturbances in cholesterol, bile acid and glucose metabolism in peroxisomal 3-ketoacylCoA thiolase B deficient mice fed diets containing high or low fat contents.
Biochimie. 2014 Mar.

Hickner S, Hussain N, Angoa-Perez M, Francescutti DM, Kuhn DM, Mateika JH.
Ventilatory long-term facilitation is evident after initial and repeated exposure to intermittent hypoxia in mice genetically depleted of brain serotonin.
J Appl Physiol (1985). 2014 Feb 1.

Nicoleta Moisoi, Valentina Fedele, Jennifer Edwards, L Miguel Martins.
Loss of PINK1 enhances neurodegeneration in a mouse model of Parkinson's disease triggered by mitochondrial stress.
Neuropharmacology. 2014 Feb.

Borroto A, Arellano I, Blanco R, Fuentes M, Orfao A, Dopfer EP, Prouza M, Suchànek M, Schamel WW, Alarcón B.
Relevance of Nck-CD3{varepsilon} Interaction for T Cell Activation In Vivo.
J Immunol. 2014 Jan 27.

Winkelmann A, Maggio N, Eller J, Caliskan G, Semtner M, Häussler U, Jüttner R, Dugladze T, Smolinsky B, Kowalczyk S, Chronowska E, Schwarz G, Rathjen FG, Rechavi G, Haas CA, Kulik A, Gloveli T, Heinemann U, Meier JC.
Changes in neural network homeostasis trigger neuropsychiatric symptoms.
J Clin Invest. 2014 Jan 16.

Fantin A, Herzog B, Mahmoud M, Yamaji M, Plein A, Denti L, Ruhrberg C, Zachary I.
Neuropilin 1 (NRP1) hypomorphism combined with defective VEGF-A binding reveals novel roles for NRP1 in developmental and pathological angiogenesis.
Development. 2014 Jan 8.

Liu S, Thompson K, Leask A.
CCN2 expression by fibroblasts is not required for cutaneous tissue repair.
Wound Repair Regen. 2014 Jan;22(1):119-24.

Grabrucker S, Proepper C, Mangus K, Eckert M, Chhabra R, Schmeisser MJ, Boeckers TM, Grabrucker AM.
The PSD protein ProSAP2/Shank3 displays synapto-nuclear shuttling which is deregulated in a schizophrenia-associated mutation.
Exp Neurol. 2013 Dec 29. pii: S0014-4886(13)00381-6.

Angoa-Pérez M, Kane MJ, Briggs DI, Francescutti DM, Kuhn DM.
Marble burying and nestlet shredding as tests of repetitive, compulsive-like behaviors in mice.
J Vis Exp. 2013 Dec 24.

Lengacher S, Nehiri-Sitayeb T, Steiner N, Carneiro L, Favrod C, Preitner F, Thorens B, Stehle JC, Dix L, Pralong F, Magistretti PJ, Pellerin L.
Resistance to diet-induced obesity and associated metabolic perturbations in haploinsufficient monocarboxylate transporter 1 mice.
PLoS One. 2013 Dec 18;8(12).

Shalata A, Ramirez MC, Desnick RJ, Priedigkeit N, Buettner C, Lindtner C, Mahroum M, Abdul-Ghani M, Dong F, Arar N, Camacho-Vanegas O, Zhang R, Camacho SC, Chen Y, Ibdah M, DeFronzo R, Gillespie V, Kelley K, Dynlacht BD, Kim S, Glucksman MJ, Borochowitz ZU, Martignetti JA.
Morbid obesity resulting from inactivation of the ciliary protein CEP19 in humans and mice.
Am J Hum Genet. 2013 Dec 5.

Lee V, Maguire J.
Impact of inhibitory constraint of interneurons on neuronal excitability.
J Neurophysiol. 2013 Dec.

Adolph TE, Tomczak MF, Niederreiter L, Ko HJ, Böck J, Martinez-Naves E, Glickman JN, Tschurtschenthaler M, Hartwig J, Hosomi S, Flak MB, Cusick JL, Kohno K, Iwawaki T, Billmann-Born S, Raine T, Bharti R, Lucius R, Kweon MN, Marciniak SJ, Choi A, Hagen SJ, Schreiber S, Rosenstiel P, Kaser A, Blumberg RS.
Paneth cells as a site of origin for intestinal inflammation.
Nature. 2013 Nov 14;503(7475):272-6.

Banning A, Regenbrecht CR, Tikkanen R.
Increased activity of mitogen activated protein kinase pathway in flotillin-2 knockout mouse model.
Cell Signal. 2013 Nov 9;26(2):198-207.

Helmer RA, Martínez-Zaguilán R, Dertien JS, Fulford C, Foreman O, Peiris V, Chilton BS.
Helicase-like transcription factor (hltf) regulates g2/m transition, wt1/gata4/hif-1a cardiac transcription networks, and collagen biogenesis.
PLoS One. 2013 Nov 20;8(11):e80461. doi: 10.1371/journal.pone.0080461.

Garanto A, van Beersum SE, Peters TA, Roepman R, Cremers FP, Collin RW.
Unexpected CEP290 mRNA Splicing in a Humanized Knock-In Mouse Model for Leber Congenital Amaurosis.
PLoS One. 2013 Nov 6;8(11):e79369. doi: 10.1371/journal.pone.0079369.

Imudia AN, Wang N, Tanaka Y, White YA, Woods DC, Tilly JL.
Comparative gene expression profiling of adult mouse ovary-derived oogonial stem cells supports a distinct cellular identity.
Fertil Steril. 2013 Nov;100(5):1451-8.

Goettsch C, Babelova A, Trummer O, Erben RG, Rauner M, Rammelt S, Weissmann N, Weinberger V, Benkhoff S, Kampschulte M, Obermayer-Pietsch B, Hofbauer LC, Brandes RP, Schröder K.
NADPH oxidase 4 limits bone mass by promoting osteoclastogenesis.
J Clin Invest. 2013 November 1; 123(11): 4731–4738.

Gulbins E, Palmada M, Reichel M, Lüth A, Böhmer C, Amato D, Müller CP, Tischbirek CH, Groemer TW, Tabatabai G, Becker KA, Tripal P, Staedtler S, Ackermann TF, van Brederode J, Alzheimer C, Weller M, Lang UE, Kleuser B, Grassmé H, Kornhuber J.
Acid sphingomyelinase-ceramide system mediates effects of antidepressant drugs.
Nat Med. 2013 Jul;19(7):934-8. doi: 10.1038/nm.3214. Epub 2013 Jun 16.

Crowe J, Aubareda A, McNamee K, Przybycien PM, Lu X, Williams RO, Bou-Gharios G, Saklatvala J, Dean JL.
Heat shock protein b1-deficient mice display impaired wound healing.
PLoS One. 2013 Oct 15;8(10):e77383. doi: 10.1371/journal.pone.0077383.

Hahm E, Li J, Kim K, Huh S, Rogelj S, Cho J.
Extracellular protein disulfide isomerase regulates ligand-binding activity of αMβ2 integrin and neutrophil recruitment during vascular inflammation.
Blood. 2013 May 9;121(19):3789-800, S1-15. doi: 10.1182/blood-2012-11-467985. Epub 2013 Mar 4.

Kim K, Hahm E, Li J, Holbrook LM, Sasikumar P, Stanley RG, Ushio-Fukai M, Gibbins JM, Cho J.
Platelet protein disulfide isomerase is required for thrombus formation but not for hemostasis in mice.
Blood. 2013 Aug 8;122(6):1052-61. doi: 10.1182/blood-2013-03-492504. Epub 2013 Jun 20.

Huntwork-Rodriguez S, Wang B, Watkins T, Ghosh AS, Pozniak CD, Bustos D, Newton K, Kirkpatrick DS, Lewcock JW.
JNK-mediated phosphorylation of DLK suppresses its ubiquitination to promote neuronal apoptosis.
J Cell Biol. 2013 Sep 2;202(5):747-63. doi: 10.1083/jcb.201303066. Epub 2013 Aug 26.

Vandenbeuch A, Anderson CB, Parnes J, Enjyoji K, Robson SC, Finger TE, Kinnamon SC.
Role of the ectonucleotidase NTPDase2 in taste bud function.
Proc Natl Acad Sci U S A. 2013 Aug 19. [Epub ahead of print]

Dart DA, Waxman J, Aboagye EO, Bevan CL.
Visualising androgen receptor activity in male and female mice.
PLoS One. 2013 Aug 7;8(8):e71694. doi: 10.1371/journal.pone.0071694. Print 2013.

Hinkel R, Penzkofer D, Zühlke S, Fischer A, Husada W, Xu QF, Baloch E, van Rooij E, Zeiher AM, Kupatt C, Dimmeler S.
Inhibition of MicroRNA-92a Protects Against Ischemia-Reperfusion Injury in a Large Animal Model.
Circulation. 2013 Jul 29. [Epub ahead of print]

Imudia AN, Wang N, Tanaka Y, White YA, Woods DC, Tilly JL.
Comparative gene expression profiling of adult mouse ovary-derived oogonial stem cells supports a distinct cellular identity.
Fertil Steril. 2013 Jul 19. pii: S0015-0282(13)00736-X. doi: 10.1016/j.fertnstert.2013.06.036. [Epub ahead of print]

Helmer RA, Foreman O, Dertien JS, Panchoo M, Bhakta SM, Chilton BS.
Role of helicase-like transcription factor (hltf) in the g2/m transition and apoptosis in brain.
PLoS One. 2013 Jun 24;8(6):e66799. doi: 10.1371/journal.pone.0066799. Print 2013.

Puszyk W, Down T, Grimwade D, Chomienne C, Oakey RJ, Solomon E, Guidez F.
The epigenetic regulator PLZF represses L1 retrotransposition in germ and progenitor cells.
EMBO J. 2013 May 31. doi: 10.1038/emboj.2013.118. [Epub ahead of print]

Sagardoy A, Martinez-Ferrandis JI, Roa S, Bunting KL, Aznar MA, Elemento O, Shaknovich R, Fontán L, Fresquet V, Perez-Roger I, Robles EF, De Smedt L, Sagaert X, Melnick A, Martinez-Climent JA.
Downregulation of FOXP1 is required during germinal center B-cell function.
Blood. 2013 May 23.

Prieur X, Dollet L, Takahashi M, Nemani M, Pillot B, Le May C, Mounier C, Takigawa-Imamura H, Zelenika D, Matsuda F, Fève B, Capeau J, Lathrop M, Costet P, Cariou B, Magré J.
Thiazolidinediones partially reverse the metabolic disturbances observed in Bscl2/seipin-deficient mice.
Diabetologia. 2013 May 17. [Epub ahead of print]

Li MM, Nilsen A, Shi Y, Fusser M, Ding YH, Fu Y, Liu B, Niu Y, Wu YS, Huang CM, Olofsson M, Jin KX, Lv Y, Xu XZ, He C, Dong MQ, Rendtlew Danielsen JM, Klungland A, Yang YG.
ALKBH4-dependent demethylation of actin regulates actomyosin dynamics.
Nat Commun. 2013;4:1832. doi: 10.1038/ncomms2863.

Mühle C, Huttner HB, Walter S, Reichel M, Canneva F, Lewczuk P, Gulbins E, Kornhuber J.
Characterization of Acid sphingomyelinase activity in human cerebrospinal fluid.
PLoS One. 2013 May 2;8(5):e62912. doi: 10.1371/journal.pone.0062912. Print 2013.

Saheb-Al-Zamani M, Yan Y, Farber SJ, Hunter DA, Newton P, Wood MD, Stewart SA, Johnson PJ, Mackinnon SE.
Limited regeneration in long acellular nerve allografts is associated with increased Schwann cell senescence.
Exp Neurol. 2013 May 2. pii: S0014-4886(13)00139-8. doi: 10.1016/j.expneurol.2013.04.011. [Epub ahead of print]

Sportoletti P, Varasano E, Rossi R, Bereshchenko O, Cecchini D, Gionfriddo I, Bolli N, Tiacci E, Intermesoli T, Zanghì P, Masciulli A, Martelli MP, Falzetti F, Martelli MF, Falini B.
The human NPM1 mutation A perturbs megakaryopoiesis in a conditional mouse model.
Blood. 2013 Apr 25.

Zeng L, Xiao Q, Chen M, Margariti A, Martin D, Ivetic A, Xu H, Mason J, Wang W, Cockerill G, Mori K, Li JY, Chien S, Hu Y, Xu Q.
Vascular endothelial cell growth-activated XBP1 splicing in endothelial cells is crucial for angiogenesis.
Circulation. 2013 Apr 23.

Ehrmann I, Dalgliesh C, Liu Y, Danilenko M, Crosier M, Overman L, Arthur HM, Lindsay S, Clowry GJ, Venables JP, Fort P, Elliott DJ.
The Tissue-Specific RNA Binding Protein T-STAR Controls Regional Splicing Patterns of Neurexin Pre-mRNAs in the Brain.
PLoS Genet. 2013 Apr;9(4):e1003474. doi: 10.1371/journal.pgen.1003474. Epub 2013 Apr 25.

Chen J, Martinez J, Milner TA, Buck J, Levin LR.
Neuronal Expression of Soluble Adenylyl Cyclase in the Mammalian Brain.
Brain Res. 2013 Apr 20. pii: S0006-8993(13)00569-6. doi: 10.1016/j.brainres.2013.04.027. [Epub ahead of print]

Pavlovic D, Hall AR, Kennington EJ, Aughton K, Boguslavskyii A, Fuller W, Despa S, Bers DM, Shattock MJ.
Nitric oxide regulates cardiac intracellular Na+ and Ca2+ by modulating Na/K ATPase via PKCε and phospholemman-dependent mechanism.
J Mol Cell Cardiol. 2013 Apr 20. pii: S0022-2828(13)00144-2. doi: 10.1016/j.yjmcc.2013.04.013. [Epub ahead of print]

Galligan JJ, Patel BA, Schneider SP, Wang H, Zhao H, Novotny M, Bian X, Kabeer R, Fried D, Swain GM.
Visceral hypersensitivity in female but not in male serotonin transporter knockout rats.
Neurogastroenterol Motil. 2013 Apr 17. doi: 10.1111/nmo.12133. [Epub ahead of print]

Solberg A, Robertson AB, Aronsen JM, Rognmo O, Sjaastad I, Wisløff U, Klungland A.
Deletion of mouse Alkbh7 leads to obesity.
J Mol Cell Biol. 2013 Apr 8. [Epub ahead of print]

Ryan D, Koss D, Porcu E, Woodcock H, Robinson L, Platt B, Riedel G.
Spatial learning impairments in PLB1Triple knock-in Alzheimer mice are task-specific and age-dependent.
Cell Mol Life Sci. 2013 Mar 28. [Epub ahead of print]

Zhang J, Twelvetrees AE, Lazarus JE, Blasier KR, Yao X, Inamdar NA, Holzbaur EL, Pfister KK, Xiang X.
Establishing a novel knock-in mouse line for studying neuronal cytoplasmic dynein under normal and pathologic conditions.
Cytoskeleton (Hoboken). 2013 Mar 8. doi: 10.1002/cm.21102. [Epub ahead of print]

Taruno A, Vingtdeux V, Ohmoto M, Ma Z, Dvoryanchikov G, Li A, Adrien L, Zhao H, Leung S, Abernethy M, Koppel J, Davies P, Civan MM, Chaudhari N, Matsumoto I, Hellekant G, Tordoff MG, Marambaud P, Foskett JK.
CALHM1 ion channel mediates purinergic neurotransmission of sweet, bitter and umami tastes.
Nature. 2013 Mar 6. doi: 10.1038/nature11906. [Epub ahead of print]

Ufartes R, Schneider T, Mortensen LS, Romero MD, Hentrich K, Knoetgen H, Beilinson V, Moebius W, Tarabykin V, Alves F, Pardo LA, Rawlins JN, Stuehmer W.
Behavioural and functional characterization of Kv10.1 (Eag1) knockout mice.
Hum Mol Genet. 2013 Feb 18. [Epub ahead of print]

Simard AR, Gan Y, St-Pierre S, Kousari A, Patel V, Whiteaker P, Morley BJ, Lukas RJ, Shi FD.
Differential modulation of EAE by α9*- and β2*-nicotinic acetylcholine receptors.
Immunol Cell Biol. 2013 Feb 12. doi: 10.1038/icb.2013.1. [Epub ahead of print]

McManaman JL, Bales ES, Orlicky DJ, Jackman M, Maclean PS, Cain S, Crunk AE, Mansur A, Graham CE, Bowman TA, Greenberg AS.
Perilipin-2 Null Mice are Protected Against Diet-Induced Obesity, Adipose Inflammation and Fatty Liver Disease.
J Lipid Res. 2013 Feb 12. [Epub ahead of print]

Villarroel-Espíndola F, Maldonado R, Mancilla H, Vander Stelt K, Acuña A, Covarrubias A, López C, Angulo C, Castro MA, Slebe JC, Durán J, García-Rocha M, Guinovart JJ, Concha II.
Muscle glycogen synthase isoform is responsible for testicular glycogen synthesis: Glycogen overproduction induces apoptosis in male germ cells.
J Cell Biochem. 2013 Feb 5. doi: 10.1002/jcb.24507. [Epub ahead of print]

Ménoret S, Fontanière S, Jantz D, Tesson L, Thinard R, Rémy S, Usal C, Ouisse LH, Fraichard A, Anegon I.
Generation of Rag1-knockout immunodeficient rats and mice using engineered meganucleases.
FASEB J. 2013 Feb;27(2):703-11. doi: 10.1096/fj.12-219907. Epub 2012 Nov 12.

Borroto A, Arellano I, Dopfer EP, Prouza M, Suchànek M, Fuentes M, Orfao A, Schamel WW, Alarcón B.
Nck Recruitment to the TCR Required for ZAP70 Activation during Thymic Development.
J Immunol. 2013 Feb 1;190(3):1103-12. doi: 10.4049/jimmunol.1202055. Epub 2012 Dec 24.

Gouri Shankar Pandey, Sandra C. Tseng, Tom E. Howard, and Zuben E. Sauna
Detection of Intracellular Factor VIII Protein in Peripheral Blood Mononuclear Cells by Flow Cytometry
BioMed Research International, 28 January 2013

Dreses-Werringloer U, Vingtdeux V, Zhao H, Chandakkar P, Davies P, Marambaud P.
CALHM1 controls Ca2+-dependent MEK/ERK/RSK/MSK signaling in neurons.
J Cell Sci. 2013 Jan 23.

Margariti A, Li H, Chen T, Martin D, Vizcay-Barrena G, Alam S, Karamariti E, Xiao Q, Zampetaki A, Zhang Z, Wang W, Jiang Z, Gao C, Ma B, Chen YG, Cockerill G, Hu Y, Xu Q, Zeng L.
XBP1 mRNA Splicing Triggers an Autophagic Response in Endothelial Cells through BECLIN-1 Transcriptional Activation.
J Biol Chem. 2013 Jan 11.

Zheng G, Dahl JA, Niu Y, Fedorcsak P, Huang CM, Li CJ, Vågbø CB, Shi Y, Wang WL, Song SH, Lu Z, Bosmans RP, Dai Q, Hao YJ, Yang X, Zhao WM, Tong WM, Wang XJ, Bogdan F, Furu K, Fu Y, Jia G, Zhao X, Liu J, Krokan HE, Klungland A, Yang YG, He C.
ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility.
Mol Cell. 2013 Jan 10.


genOway is the author of the following publications:

Remy S, Tesson L, Menoret S, Usal C, De Cian A, Thepenier V, Thinard R, Baron D, Charpentier M, Renaud JB, Buelow R, Cost GJ, Giovannangeli C, Fraichard A, Concordet JP, Anegon I.
Efficient gene targeting by homology-directed repair in rat zygotes using TALE nucleases.
Genome Res. 2014 Jul 2.

Ménoret S, Fontanière S, Jantz D, Tesson L, Thinard R, Rémy S, Usal C, Ouisse LH, Fraichard A, Anegon I.
Generation of Rag1-knockout immunodeficient rats and mice using engineered meganucleases.
FASEB J. 2012 Nov 12. [Epub ahead of print]

Satoh-Takayama N, Vosshenrich CA, Lesjean-Pottier S, Sawa S, Lochner M, Rattis F, Mention JJ, Thiam K, Cerf-Bensussan N, Mandelboim O, Eberl G, Di Santo JP.
Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense.
Immunity. 2008 Dec 19;29(6):958-70. doi: 10.1016/j.immuni.2008.11.001. Epub 2008 Dec 11.

Cozzi J, Fraichard A, Thiam K.
Use of genetically modified rat models for translational medicine.
Drug Discov Today 2008; 13: 488-494.

Tesson L, Cozzi J, Menoret S, Remy S, Usal C, Fraichard A, Anegon I.
Transgenic modifications of the rat genome.
Transgenic Res. 2005 Oct;14(5):531-46.

Zhou Q, Renard JP, Le Friec G, Brochard V, Beaujean N, Cherifi Y, Fraichard A, Cozzi J.
Generation of fertile cloned rats by regulating oocyte activation.
Science. 2003 Nov 14;302(5648):1179. Epub 2003 Sep 25.

Article in Book:

"Procedures for somatic cell nuclear transfer in the rat" Jean Cozzi, Eryao Wang, Christelle Jacquet, Alexandre Fraichard, Yacine Cherifi, Qi Zhou. Methods and Protocols, Methods in Molecular Biology, vol 597, Humana Press 2010

"Interference RNA for in vivo knock-down of gene expression or genome-wide screening using shRNA". Petit S, Thiam K. In: Anegon (ed.). Rat genomics: Methods and Protocols, Methods in Molecular Biology, vol 597, @ Humana Press 2010

"Pronuclear DNA injection for the production of transgenic rats". Cozzi J, Fraichard A, Braun V, Gross A-C, Merrouche C, Anegon I, Thiam K. In: Transgenesis, Third Edition. 2008

"in vivo RNA interference: another tool in the Box?" in Non-viral Gene Therapy - Gene design and Delivery. Taira, K.; Kataoka, K.; Niidome, T. (Eds.) @ Springer-verlag Tokyo 2005