Publications 2009

genOway has been acknowledged in numerous articles for the generation of both mouse/rat models. Below, a selection of these publications:


Bujakowska K, Maubaret C, Chakarova CF, Tanimoto N, Beck SC, Fahl E, Humphries MM, Kenna PF, Makarov E, Makarova O, Paquet-Durand F, Ekström PA, van Veen T, Leveillard T, Humphries P, Seeliger MW, Bhattacharya SS.
Study of gene-targeted mouse models of splicing factor gene Prpf31 implicated in human autosomal dominant retinitis pigmentosa (RP).
Invest Ophthalmol Vis Sci. 2009 Dec;50(12):5927-33.

Steinmetz OM, Turner JE, Paust HJ, Lindner M, Peters A, Heiss K, Velden J, Hopfer H, Fehr S, Krieger T, Meyer-Schwesinger C, Meyer TN, Helmchen U, Mittrücker HW, Stahl RA, Panzer U.
CXCR3 mediates renal Th1 and Th17 immune response in murine lupus nephritis.
J Immunol. 2009 Oct 1;183(7):4693-704.

Favaro R, Valotta M, Ferri AL, Latorre E, Mariani J, Giachino C, Lancini C, Tosetti V, Ottolenghi S, Taylor V, Nicolis SK.
Hippocampal development and neural stem cell maintenance require Sox2-dependent regulation of Shh.
Nat Neurosci. 2009 Oct;12(10):1248-56. doi: 10.1038/nn.2397. Epub 2009 Sep 6.

Wirths O, Breyhan H, Cynis H, Schilling S, Demuth HU, Bayer TA.
Intraneuronal pyroglutamate-Abeta 3-42 triggers neurodegeneration and lethal neurological deficits in a transgenic mouse model.
Acta Neuropathol. 2009 Oct;118(4):487-96.

David V, Martin A, Hedge AM, Rowe PS.
Matrix extracellular phosphoglycoprotein (MEPE) is a new bone renal hormone and vascularization modulator.
Endocrinology. 2009 Sep;150(9):4012-23.

Lemaire K, Ravier MA, Schraenen A, Creemers JW, Van de Plas R, Granvik M, Van Lommel L, Waelkens E, Chimienti F, Rutter GA, Gilon P, in't Veld PA, Schuit FC.
Insulin crystallization depends on zinc transporter ZnT8 expression, but is not required for normal glucose homeostasis in mice.
Proc Natl Acad Sci U S A. 2009 Sep 1;106(35):14872-7.

Nicolson TJ, Bellomo EA, Wijesekara N, Loder MK, Baldwin JM, Gyulkhandanyan AV, Koshkin V, Tarasov AI, Carzaniga R, Kronenberger K, Taneja TK, da Silva Xavier G, Libert S, Froguel P, Scharfmann R, Stetsyuk V, Ravassard P, Parker H, Gribble FM, Reimann F, Sladek R, Hughes SJ, Johnson PR, Masseboeuf M, Burcelin R, Baldwin SA, Liu M, Lara-Lemus R, Arvan P, Schuit FC, Wheeler MB, Chimienti F, Rutter GA.
Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants.
Diabetes. 2009 Sep;58(9):2070-83.

Johswich K, Martin M, Bleich A, Kracht M, Dittrich-Breiholz O, Gessner JE, Suerbaum S, Wende E, Rheinheimer C, Klos A.
Role of the C5a receptor (C5aR) in acute and chronic dextran sulfate-induced models of inflammatory bowel disease.
Inflamm Bowel Dis. 2009 Aug 27;15(12):1812-1823.

Chistiakov DA, Voronova NV.
Zn(2+)-transporter-8: a dual role in diabetes.
Biofactors. 2009 Jul-Aug;35(4):356-63.

Pushparaj PN, Manikandan J, Tay HK, H'ng SC, Kumar SD, Pfeilschifter J, Huwiler A, Melendez AJ.
Sphingosine kinase 1 is pivotal for Fc epsilon RI-mediated mast cell signaling and functional responses in vitro and in vivo.
J Immunol. 2009 Jul 1;183(1):221-7.

Linder AE, Beggs KM, Burnett RJ, Watts SW.
Body distribution of infused serotonin in rats.
Clin Exp Pharmacol Physiol. 2009 May;36(5-6):599-601. doi: 10.1111/j.1440-1681.2009.05147.x. Epub 2009 Jan 18.

Dobbertin A, Hrabovska A, Dembele K, Camp S, Taylor P, Krejci E, Bernard V.
Targeting of acetylcholinesterase in neurons in vivo: a dual processing function for the proline-rich membrane anchor subunit and the attachment domain on the catalytic subunit.
J Neurosci. 2009 Apr 8;29(14):4519-30.

Guyon A, Tardy MP, Rovère C, Nahon JL, Barhanin J, Lesage F.
Glucose inhibition persists in hypothalamic neurons lacking tandem-pore K+ channels.
J Neurosci. 2009 Feb 25;29(8):2528-33.