Genetically Engineered Cell Lines
Our CRISPR/Cas9 gene-editing platform for customized cell line development is optimized for mammalian and human cells.
A major benefit for you and your research is our rigorous procedure to quickly evaluate the feasibility of using your proper cell line. Our genetic modifications to your chosen in-house cell line optimize the use of your existing data and avoid the need for new standardization experiments.
We ensure reliable and reproducible performance in murine or human:
- Cancer, cardiovascular disease, diabetes, respiratory, and musculoskeletal cell lines
- Embryonic stem, induced pluripotent stem, neural stem cell, and more
Our cell line services
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Permanent inactivation of the target gene, and total absence of the protein
Point mutation Knockins
One or more constitutively mutated nucleotides affecting the function of a given protein (gain/loss of function)
With inserted fluorescent, bioluminescent proteins or biochemical tags
Controlled gene expression by targeting permissive loci Rosa26, Hprt or AAVS1
Add a gene sequence of interest to an endogenous locus
Learn more about our cell line engineering service:
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