Lrig1 conditional Knockout mouse

Target

Gene symbol :

Lrig1

NCBI gene ID :

16206

Gene full name :

Leucine-rich repeats and immunoglobulin-like domains 1

Synonym :

LRIG1

Protein function

Protein name :

LRIG1

Transmembrane protein that negatively regulates receptor tyrosine kinases, involved in stem cell maintenance.

Expected phenotype

Altered stem cell homeostasis and increased susceptibility to tumorigenesis.

Human disease relevance

Linked to various cancers and epidermal appendage tumors.

Model applications

Research on stem cell biology and cancer.

Keywords:

RTK regulation, Stem cells, Tumor suppressor

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
WoldWide delivery by professional breeders

Lrig1

conditional Knockout mouse

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hPD-1 hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.

hPD-1 hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.

hPD-1 hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.

hPD-1 hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.