Traditionally, transgenic rats refer to genetically modified (GM) models in which the genome has been altered through random integration of gene sequences.

Today, the wording is used in a broader sense for targeted gene mutations, like:

  • Deletion (Knockout)
  • Insertion/amplification (Knockin)
  • Substitution (e.g., point mutation Knockin)

Since 2002, we have been heavily investing in Knockout/Knockin rat model development, and have designed a unique CRISPR/Cas9-based offer, combining our:

  • Expertise in model design
  • Rigorous quality controls for rat models

With the advantages of gene CRISPR/Cas9 technology, such as:

  • Cost effectiveness
  • Short development time

Your benefits and guarantees:

  • Robust design for physiological relevant rat models
  • Reliable and reproducible performance in many rat strains, including, but not limited to:
  • Inbred: Brown Norway, Fischer 344, Lewis, etc.
  • Outbred: Wistar, Long-Evans, Spraque Dawley, etc.
  • Freedom to operate thanks to our unique IP portfolio, including licenses from MIT and Merck KGaA
  • Rigorous off-target assessment
More info

Transgenic rat models

Get in touch about

Let us know how we can help

Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe