Traditionally, transgenic rats refer to genetically modified (GM) models in which the genome has been altered through random integration of gene sequences.
Today, the wording is used in a broader sense for targeted gene mutations, like:
- Deletion (Knockout)
- Insertion/amplification (Knockin)
- Substitution (e.g., point mutation Knockin)
Since 2002, we have been heavily investing in Knockout/Knockin rat model development, and have designed a unique CRISPR/Cas9-based offer, combining our:
- Expertise in model design
- Rigorous quality controls for rat models
With the advantages of gene CRISPR/Cas9 technology, such as:
- Cost effectiveness
- Short development time
Your benefits and guarantees:
- Robust design for physiological relevant rat models
- Reliable and reproducible performance in many rat strains, including, but not limited to:
- Inbred: Brown Norway, Fischer 344, Lewis, etc.
- Outbred: Wistar, Long-Evans, Spraque Dawley, etc.
- Freedom to operate thanks to our unique IP portfolio, including licenses from MIT and Merck KGaA
- Rigorous off-target assessment


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