Target

Gene symbol :  
Aldh2
NCBI gene ID :  
11669
Gene full name :  
Aldehyde dehydrogenase 2
Synonym :  
Aldh-E2, RALDH2

Protein function

Protein name :  
ALDH2
Detoxifies aldehydes from ethanol metabolism and oxidative stress.

Expected phenotype

Increased oxidative damage, ethanol sensitivity

Human disease relevance

Linked to alcohol flushing, cardiovascular disease

Model applications

Alcohol metabolism, oxidative stress

Keywords:

Acetaldehyde, ROS, Ethanol metabolism

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • WoldWide delivery by professional breeders

Aldh2

conditional Knockout mouse

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