Ampd2 conditional Knockout mouse

Target

Gene symbol :

Ampd2

NCBI gene ID :

109674

Gene full name :

Adenosine monophosphate deaminase 2

Synonym :

—

Protein function

Protein name :

AMP deaminase 2

Catalyzes deamination of AMP to IMP in energy metabolism; heart- and kidney-enriched

Expected phenotype

Knockouts show cardiac and renal function defects under stress

Human disease relevance

Mutations linked to pontocerebellar hypoplasia and metabolic syndromes

Model applications

Studied in purine metabolism and cardiometabolic disorders

Keywords:

Purine metabolism, Energy balance, AMP deaminase, Cardiac

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Ampd2

conditional Knockout mouse

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