Target

Gene symbol :  
Arap2
NCBI gene ID :  
212285
Gene full name :  
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
Synonym :  
Centd3

Protein function

Protein name :  
ARAP2 protein
GTPase-activating protein for ARF6; regulates actin cytoskeleton and endocytosis

Expected phenotype

Altered integrin recycling and cytoskeleton in knockdowns

Human disease relevance

Implicated in cancer cell motility and adhesion

Model applications

Studied in membrane trafficking and actin remodeling

Keywords:

ARF signaling, RhoGAP, Cytoskeleton, Cell migration

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Arap2

conditional Knockout mouse

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