Arhgap17 conditional Knockout mouse

Target

Gene symbol :

Arhgap17

NCBI gene ID :

70497

Gene full name :

Rho GTPase activating protein 17

Synonym :

Nadrin, Nadrin1

Protein function

Protein name :

Rho GTPase-activating protein 17

Regulates actin cytoskeleton via Rho GTPase signaling; involved in cell polarity and junctions

Expected phenotype

Knockouts affect intestinal barrier function and actin organization

Human disease relevance

Implicated in inflammatory bowel disease and epithelial dysfunction

Model applications

Used in actin signaling and intestinal epithelial barrier studies

Keywords:

RhoGAP, Actin, Tight junctions, IBD

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Arhgap17

conditional Knockout mouse

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