Target

Gene symbol :  
Arpin
NCBI gene ID :  
70420
Gene full name :  
Actin related protein 2/3 complex inhibitor
Synonym :  
Arp-inhibitor

Protein function

Protein name :  
Arpin
Inhibits Arp2/3 complex; controls actin branching and cell migration

Expected phenotype

Knockouts show increased cell motility and directional persistence

Human disease relevance

Altered expression in cancer invasion and metastasis

Model applications

Studied in cell motility, cytoskeletal remodeling, and cancer

Keywords:

Actin, Arp2/3, Cell migration, Cancer invasion

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Arpin

conditional Knockout mouse

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