Aspn conditional Knockout mouse

Target

Gene symbol :

Aspn

NCBI gene ID :

66695

Gene full name :

Asporin

Synonym :

Asporin, PLAP1

Protein function

Protein name :

ASPN

ECM protein in cartilage; regulates collagen fibrillogenesis and TGF-β signaling

Expected phenotype

Cartilage defects, skeletal anomalies

Human disease relevance

Associated with osteoarthritis and skeletal dysplasia

Model applications

Cartilage and bone formation models

Keywords:

ECM, Cartilage, Collagen binding

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Aspn

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe