Target

Gene symbol :  
Cbx1
NCBI gene ID :  
12412
Gene full name :  
Chromobox 1
Synonym :  
HP1β

Protein function

Protein name :  
CBX1
Binds methylated histones (H3K9me3) to promote heterochromatin formation.

Expected phenotype

Epigenetic dysregulation

Human disease relevance

Involved in chromatin silencing and cancer

Model applications

Epigenetics, gene repression

Keywords:

HP1, Chromatin, H3K9 methylation

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Cbx1

conditional Knockout mouse

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