Cc2d2a conditional Knockout mouse

Target

Gene symbol :

Cc2d2a

NCBI gene ID :

231214

Gene full name :

Coiled-coil and C2 domain containing 2A

Synonym :

—

Protein function

Protein name :

CC2D2A protein

Centrosome and basal body protein; important for cilia formation

Expected phenotype

KO shows ciliopathy-like phenotypes including hydrocephalus

Human disease relevance

Mutations cause Meckel and Joubert syndromes

Model applications

Used in ciliopathy and neural development models

Keywords:

Ciliogenesis, Basal body, Meckel syndrome, Joubert syndrome

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Cc2d2a

conditional Knockout mouse

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