Cd28 conditional Knockout mouse

Target

Gene symbol :

Cd28

NCBI gene ID :

12487

Gene full name :

CD28 antigen

Synonym :

T-cell co-stimulatory molecule

Protein function

Protein name :

CD28

Co-stimulatory receptor on T cells essential for full activation and survival.

Expected phenotype

Deficient T-cell activation and memory response

Human disease relevance

Targeted in immunotherapy and transplant biology

Model applications

T-cell co-stimulation, immune checkpoint

Keywords:

TCR signaling, CD80/86, T-cell activation

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Cd28

conditional Knockout mouse

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