Cenpj conditional Knockout mouse

Target

Gene symbol :

Cenpj

NCBI gene ID :

219103

Gene full name :

Centromere protein J

Synonym :

Sas4, CPAP

Protein function

Protein name :

Centrosomal P4.1-associated protein

Essential for centriole biogenesis and centrosome integrity

Expected phenotype

KO mice show microcephaly, disrupted mitosis

Human disease relevance

Mutations cause primary microcephaly (MCPH6)

Model applications

Studied in neurodevelopment and centriole biology

Keywords:

Centriole, Microcephaly, Centrosome, Cell division

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Cenpj

conditional Knockout mouse

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Easy access to models

Models with certified health status from professional breeders in US and Europe