Cenpl conditional Knockout mouse

Target

Gene symbol :

Cenpl

NCBI gene ID :

70454

Gene full name :

Centromere protein L

Synonym :

CENP-L

Protein function

Protein name :

Centromere protein L

Component of the CENP-H/I complex; required for kinetochore assembly and chromosome segregation

Expected phenotype

Knockouts result in early embryonic lethality

Human disease relevance

Disruption may lead to chromosomal instability in cancer

Model applications

Used in mitosis and centromere function studies

Keywords:

Kinetochore, Chromosome segregation, Mitosis, Centromere

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Cenpl

conditional Knockout mouse

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