Target

Gene symbol :  
Chtop
NCBI gene ID :  
66511
Gene full name :  
Chromatin target of PRMT1
Synonym :  
Chromatin target of PRMT1, C20orf77 ortholog

Protein function

Protein name :  
CHTOP
Regulates RNA export, chromatin architecture, and gene expression

Expected phenotype

Gene expression dysregulation, developmental defects

Human disease relevance

Often dysregulated in cancer

Model applications

Epigenetics and RNA processing models

Keywords:

RNA export, Chromatin, Epigenetics

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Chtop

conditional Knockout mouse

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