Target

Gene symbol :  
Clcnka
NCBI gene ID :  
12733
Gene full name :  
Chloride voltage-gated channel Ka
Synonym :  
CLC-Ka, Clcnk1

Protein function

Protein name :  
CLCNKA
Kidney-specific chloride channel involved in salt balance and urine concentration.

Expected phenotype

Electrolyte imbalance, renal dysfunction

Human disease relevance

Implicated in Bartter syndrome

Model applications

Renal physiology, electrolyte transport

Keywords:

Chloride channel, Kidney, Bartter syndrome

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Clcnka

conditional Knockout mouse

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