Clcnka conditional Knockout mouse

Target

Gene symbol :

Clcnka

NCBI gene ID :

12733

Gene full name :

Chloride voltage-gated channel Ka

Synonym :

CLC-Ka, Clcnk1

Protein function

Protein name :

CLCNKA

Kidney-specific chloride channel involved in salt balance and urine concentration.

Expected phenotype

Electrolyte imbalance, renal dysfunction

Human disease relevance

Implicated in Bartter syndrome

Model applications

Renal physiology, electrolyte transport

Keywords:

Chloride channel, Kidney, Bartter syndrome

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Clcnka

conditional Knockout mouse

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