Target

Gene symbol :  
Cotl1
NCBI gene ID :  
72042
Gene full name :  
Coactosin-like protein
Synonym :  
Clp, CLP1

Protein function

Protein name :  
Coactosin-like protein
Binds F-actin and 5-lipoxygenase; modulates actin dynamics and inflammation

Expected phenotype

Knockout affects leukocyte motility and inflammatory signaling

Human disease relevance

Involved in asthma, inflammation, and immune signaling pathways

Model applications

Studied in actin regulation and leukocyte biology

Keywords:

Actin, Inflammation, 5-LO, Immune response

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Cotl1

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe