Ddah1 conditional Knockout mouse

Target

Gene symbol :

Ddah1

NCBI gene ID :

69219

Gene full name :

Dimethylarginine dimethylaminohydrolase 1

Synonym :

DDAH, Ddah

Protein function

Protein name :

Dimethylarginine dimethylaminohydrolase 1

Hydrolyzes asymmetric dimethylarginine (ADMA), a nitric oxide synthase inhibitor; regulates NO signaling

Expected phenotype

Knockout mice show elevated ADMA levels, altered vascular tone

Human disease relevance

Linked to cardiovascular diseases and endothelial dysfunction

Model applications

Used in models of cardiovascular regulation, hypertension, and endothelial biology

Keywords:

Nitric oxide, Endothelium, ADMA, Cardiovascular

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Ddah1

conditional Knockout mouse

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