Dsc3 conditional Knockout mouse

Target

Gene symbol :

Dsc3

NCBI gene ID :

13507

Gene full name :

Desmocollin 3

Synonym :

Desmocollin-3, Cadherin family member 3

Protein function

Protein name :

DSC3

Calcium-dependent adhesion molecule of epithelial desmosomes.

Expected phenotype

Epithelial fragility, hair defects

Human disease relevance

Mutated in skin fragility disorders and cancers

Model applications

Skin barrier modeling, desmosome function

Keywords:

Cadherin, Adhesion, Desmosome

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Dsc3

conditional Knockout mouse

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