Target

Gene symbol :  
Dsc3
NCBI gene ID :  
13507
Gene full name :  
Desmocollin 3
Synonym :  
Desmocollin-3, Cadherin family member 3

Protein function

Protein name :  
DSC3
Calcium-dependent adhesion molecule of epithelial desmosomes.

Expected phenotype

Epithelial fragility, hair defects

Human disease relevance

Mutated in skin fragility disorders and cancers

Model applications

Skin barrier modeling, desmosome function

Keywords:

Cadherin, Adhesion, Desmosome

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Dsc3

conditional Knockout mouse

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