Eif2b1 conditional Knockout mouse

Target

Gene symbol :

Eif2b1

NCBI gene ID :

209354

Gene full name :

Eukaryotic translation initiation factor 2B subunit alpha

Synonym :

—

Protein function

Protein name :

eIF2B subunit alpha

Regulates translation initiation via guanine nucleotide exchange on eIF2

Expected phenotype

KO models affect protein synthesis and stress responses

Human disease relevance

Mutations in other EIF2B subunits cause leukodystrophy; EIF2B1 role still under study

Model applications

Used in studies of translational control and cellular stress

Keywords:

Translation initiation, eIF2 complex, Stress response, Protein synthesis

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Eif2b1

conditional Knockout mouse

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