Epas1 conditional Knockout mouse

Target

Gene symbol :

Epas1

NCBI gene ID :

13819

Gene full name :

Endothelial PAS domain protein 1

Synonym :

Hif-2α, HIF2A, MOP2

Protein function

Protein name :

EPAS1

Hypoxia-inducible transcription factor regulating erythropoiesis and angiogenesis.

Expected phenotype

Impaired oxygen sensing, vascular abnormalities

Human disease relevance

Linked to tumors, high-altitude adaptation

Model applications

Hypoxia models, erythropoiesis

Keywords:

HIF, Oxygen sensing, Angiogenesis

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Epas1

conditional Knockout mouse

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