Fanci conditional Knockout mouse

Target

Gene symbol :

Fanci

NCBI gene ID :

208836

Gene full name :

FA complementation group I

Synonym :

Fanconi anemia group I protein

Protein function

Protein name :

Fanconi anemia group I protein

Involved in DNA interstrand crosslink repair via the Fanconi anemia pathway

Expected phenotype

Knockouts show chromosomal instability and hypersensitivity to DNA damage

Human disease relevance

Mutations cause Fanconi anemia subtype I

Model applications

Studied in DNA repair, genome stability, and cancer susceptibility

Keywords:

DNA repair, Fanconi anemia, Genome maintenance, Chromosomal stability

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Fanci

conditional Knockout mouse

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