Fbxo7 conditional Knockout mouse

Target

Gene symbol :

Fbxo7

NCBI gene ID :

69754

Gene full name :

F-box protein 7

Synonym :

F-box only protein 7

Protein function

Protein name :

F-box only protein 7

Component of SCF E3 ubiquitin ligase complex; regulates mitophagy and cell cycle

Expected phenotype

Knockout shows anemia, male infertility, and mitochondrial dysfunction

Human disease relevance

Associated with Parkinson’s disease and cancer

Model applications

Used in studies of mitophagy, neurodegeneration, and spermatogenesis

Keywords:

Ubiquitin ligase, Parkinson’s, Mitophagy, Cell cycle

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Fbxo7

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe