Gad2 conditional Knockout mouse

Target

Gene symbol :

Gad2

NCBI gene ID :

14417

Gene full name :

Glutamate decarboxylase 2

Synonym :

GAD65, Glutamate decarboxylase 2

Protein function

Protein name :

GAD65

Catalyzes conversion of glutamate to GABA in inhibitory neurons.

Expected phenotype

Reduced GABA levels, seizures

Human disease relevance

Target in epilepsy, type 1 diabetes autoimmunity

Model applications

GABA signaling, autoimmune diabetes

Keywords:

GAD65, Neurotransmitter, GABA

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Gad2

conditional Knockout mouse

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