Target

Gene symbol :  
Gad2
NCBI gene ID :  
14417
Gene full name :  
Glutamate decarboxylase 2
Synonym :  
GAD65, Glutamate decarboxylase 2

Protein function

Protein name :  
GAD65
Catalyzes conversion of glutamate to GABA in inhibitory neurons.

Expected phenotype

Reduced GABA levels, seizures

Human disease relevance

Target in epilepsy, type 1 diabetes autoimmunity

Model applications

GABA signaling, autoimmune diabetes

Keywords:

GAD65, Neurotransmitter, GABA

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Gad2

conditional Knockout mouse

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