Grm6 conditional Knockout mouse

Target

Gene symbol :

Grm6

NCBI gene ID :

108072

Gene full name :

Glutamate receptor, metabotropic 6

Synonym :

mGluR6

Protein function

Protein name :

Metabotropic glutamate receptor 6

G-protein coupled receptor mediating ON-bipolar cell response in retina

Expected phenotype

Knockouts show impaired visual signaling and night blindness

Human disease relevance

Mutations cause congenital stationary night blindness (CSNB1B)

Model applications

Studied in retinal signaling and glutamate pathways

Keywords:

Retina, Glutamate receptor, GPCR, Vision

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Grm6

conditional Knockout mouse

Get in touch about

Let us know how can help

Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe