Gsk3a conditional Knockout mouse

Target

Gene symbol :

Gsk3a

NCBI gene ID :

606496

Gene full name :

Glycogen synthase kinase 3 alpha

Synonym :

Gsk3-alpha

Protein function

Protein name :

Glycogen synthase kinase-3 alpha

Ser/Thr kinase regulating glycogen metabolism, Wnt signaling, cell survival

Expected phenotype

Knockouts show glucose metabolism defects, reduced fertility

Human disease relevance

Linked to diabetes, neurodegeneration, and psychiatric disorders

Model applications

Model in signaling pathways, metabolic and neurodegenerative diseases

Keywords:

Kinase, Wnt, Insulin signaling, Metabolism, Neurobiology

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Gsk3a

conditional Knockout mouse

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