Ido2 conditional Knockout mouse

Target

Gene symbol :

Ido2

NCBI gene ID :

209176

Gene full name :

Indoleamine 2,3-dioxygenase 2

Synonym :

—

Protein function

Protein name :

Indoleamine 2,3-dioxygenase 2

Catalyzes tryptophan degradation in immune modulation and tolerance

Expected phenotype

Knockouts show altered immune responses and susceptibility to autoimmunity

Human disease relevance

Implicated in immune escape in cancer and inflammatory diseases

Model applications

Used in immunometabolism and cancer immunology studies

Keywords:

Tryptophan metabolism, Immune tolerance, IDO pathway, Immunoregulation

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Ido2

conditional Knockout mouse

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