Target

Gene symbol :  
Il22ra1
NCBI gene ID :  
230828
Gene full name :  
Interleukin 22 receptor, alpha 1
Synonym :  
IL-22R, Il22r

Protein function

Protein name :  
Interleukin-22 receptor subunit alpha-1
Binds IL-22; activates STAT signaling; mediates mucosal immunity

Expected phenotype

KO mice show altered immune responses and epithelial defense

Human disease relevance

Implicated in IBD, psoriasis, and infections

Model applications

Studied in mucosal immunity and cytokine signaling

Keywords:

Cytokine receptor, IL-22, Inflammation, Epithelial immunity

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Il22ra1

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe