Il23r conditional Knockout mouse

Target

Gene symbol :

Il23r

NCBI gene ID :

209590

Gene full name :

Interleukin 23 receptor

Synonym :

—

Protein function

Protein name :

Interleukin-23 receptor

Receptor for IL-23; essential for Th17 cell development and pro-inflammatory signaling

Expected phenotype

Knockouts lack Th17 response and show resistance to autoimmune inflammation

Human disease relevance

Associated with IBD, psoriasis, and other autoimmune diseases

Model applications

Studied in autoimmune and inflammatory disease models

Keywords:

IL-23 signaling, Th17, Autoimmunity, Cytokine receptor

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Il23r

conditional Knockout mouse

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