Il31ra conditional Knockout mouse

Target

Gene symbol :

Il31ra

NCBI gene ID :

218624

Gene full name :

Interleukin 31 receptor A

Synonym :

Glmr, IL-31 receptor subunit alpha

Protein function

Protein name :

IL-31 receptor subunit alpha

Receptor for IL-31; mediates itch and inflammatory responses

Expected phenotype

KO mice show reduced skin inflammation in models

Human disease relevance

Linked to atopic dermatitis and pruritus in humans

Model applications

Studied in inflammatory skin diseases and cytokine signaling

Keywords:

Cytokine receptor, IL-31, Pruritus, Inflammation, Dermatitis

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Il31ra

conditional Knockout mouse

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Easy access to models

Models with certified health status from professional breeders in US and Europe