Itgae conditional Knockout mouse

Target

Gene symbol :

Itgae

NCBI gene ID :

16407

Gene full name :

Integrin alpha E

Synonym :

CD103

Protein function

Protein name :

Integrin alpha-E

Mediates adhesion of intra-epithelial T-lymphocytes to epithelial cells via E-cadherin binding.

Expected phenotype

Altered immune cell localization and function.

Human disease relevance

Implicated in inflammatory bowel disease and graft-versus-host disease.

Model applications

Studies on mucosal immunity and T-cell localization.

Keywords:

Integrin, T-cell adhesion, Mucosal immunity

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
WoldWide delivery by professional breeders

Itgae

conditional Knockout mouse

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hPD-1 hLAG3

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hPD-1 hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.

hPD-1 hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.

hPD-1 hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.