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Conditional Knockout mice
Kcnj11

Kcnj11 conditional Knockout mouse

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Target

Gene symbol :  
Kcnj11
NCBI gene ID :  
16514
Gene full name :  
Potassium inwardly-rectifying channel, subfamily J, member 11
Synonym :  
Kir6.2

Protein function

Protein name :  
Kir6.2
Forms ATP-sensitive potassium channels regulating insulin secretion in pancreatic beta cells.

Expected phenotype

Impaired glucose-stimulated insulin secretion.

Human disease relevance

Mutations cause neonatal diabetes mellitus.

Model applications

Studies on insulin secretion and diabetes.

Keywords:

ATP-sensitive channel, Insulin regulation, Diabetes

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • WoldWide delivery by professional breeders

Kcnj11

conditional Knockout mouse

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hPD-1
hLAG3

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hPD-1
hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.

hPD-1
hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.

hPD-1
hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.