Kdm4b conditional Knockout mouse

Target

Gene symbol :

Kdm4b

NCBI gene ID :

193796

Gene full name :

Lysine demethylase 4B

Synonym :

Jmjd2b

Protein function

Protein name :

Histone demethylase KDM4B

Demethylates H3K9me3 and H3K36me3; regulates gene expression and cell fate

Expected phenotype

Knockouts show defects in embryonic development and stem cell differentiation

Human disease relevance

Implicated in cancer, especially hormone-related tumors

Model applications

Studied in epigenetics, development, and tumor biology

Keywords:

Histone demethylase, Epigenetics, JmjC domain, Cancer

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Kdm4b

conditional Knockout mouse

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