Kptn conditional Knockout mouse

Target

Gene symbol :

Kptn

NCBI gene ID :

70394

Gene full name :

Kaptin, actin-binding protein

Synonym :

Kaptin

Protein function

Protein name :

Kaptin

Actin-binding protein involved in cytoskeletal regulation and neuronal morphology

Expected phenotype

Knockouts show brain size reduction and behavioral abnormalities

Human disease relevance

Linked to macrocephaly and intellectual disability syndromes

Model applications

Used in models of brain development and neurogenetic disorders

Keywords:

Actin, Neurodevelopment, Macrocephaly, Behavior

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Kptn

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe