Me2 conditional Knockout mouse

Target

Gene symbol :

Me2

NCBI gene ID :

107029

Gene full name :

Malic enzyme 2, NAD(+)-dependent, mitochondrial

Synonym :

NAD-ME2

Protein function

Protein name :

NAD-dependent malic enzyme 2

Mitochondrial enzyme converting malate to pyruvate; links TCA cycle and lipid biosynthesis

Expected phenotype

Knockouts impact energy metabolism and mitochondrial function

Human disease relevance

Implicated in cancer metabolism and insulin regulation

Model applications

Studied in metabolic regulation and mitochondrial energetics

Keywords:

Malic enzyme, Mitochondria, Metabolism, TCA cycle

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Me2

conditional Knockout mouse

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