Myh14 conditional Knockout mouse

Target

Gene symbol :

Myh14

NCBI gene ID :

71960

Gene full name :

Myosin, heavy polypeptide 14

Synonym :

Myosin IIIC, NMHCII-C

Protein function

Protein name :

Myosin-14 (non-muscle myosin heavy chain IIC)

Cytoskeletal motor protein involved in cell motility and auditory function

Expected phenotype

Mutants show hearing loss and vestibular dysfunction

Human disease relevance

Mutations linked to autosomal dominant hearing loss (DFNA4B)

Model applications

Model for non-muscle myosin function and sensory disorders

Keywords:

Myosin, Hearing, Cytoskeleton, Motor protein

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Myh14

conditional Knockout mouse

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