Nadk2 conditional Knockout mouse

Target

Gene symbol :

Nadk2

NCBI gene ID :

68646

Gene full name :

NAD kinase 2, mitochondrial

Synonym :

NADK-M, mNADK2

Protein function

Protein name :

Mitochondrial NAD kinase 2

Catalyzes phosphorylation of NAD to NADP in mitochondria; regulates redox balance

Expected phenotype

Impaired NADP(H) homeostasis, metabolic stress sensitivity

Human disease relevance

Linked to neurometabolic disorders, including progressive encephalopathy

Model applications

Used to study mitochondrial redox metabolism and NADP(H) balance

Keywords:

NADP metabolism, Redox, Mitochondria, Encephalopathy

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Nadk2

conditional Knockout mouse

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