Ncaph conditional Knockout mouse

Target

Gene symbol :

Ncaph

NCBI gene ID :

215387

Gene full name :

Non-SMC condensin I complex subunit H

Synonym :

—

Protein function

Protein name :

Condensin complex subunit H

Structural component of the condensin I complex; essential for mitotic chromosome condensation

Expected phenotype

KO leads to embryonic lethality and chromosome missegregation

Human disease relevance

Dysregulation associated with chromosomal instability in cancer

Model applications

Studied in mitosis, chromatin structure, and cancer models

Keywords:

Chromosome condensation, Mitosis, Condensin, Genome integrity

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Ncaph

conditional Knockout mouse

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