Target

Gene symbol :  
Nucks1
NCBI gene ID :  
98415
Gene full name :  
Nuclear casein kinase and cyclin-dependent kinase substrate 1
Synonym :  
NUCKS

Protein function

Protein name :  
Nuclear ubiquitous casein and cyclin-dependent substrate 1
Chromatin-associated protein involved in DNA repair and cell cycle regulation

Expected phenotype

Knockouts affect DNA repair capacity and proliferation

Human disease relevance

Linked to schizophrenia and various cancers

Model applications

Used in DNA repair and transcription regulation studies

Keywords:

DNA repair, Chromatin, Cell cycle, Cancer

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Nucks1

conditional Knockout mouse

Get in touch about

Let us know how can help
Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe