Target

Gene symbol :  
Nup35
NCBI gene ID :  
69482
Gene full name :  
Nucleoporin 35
Synonym :  
Nup53

Protein function

Protein name :  
Nucleoporin Nup35
Component of the nuclear pore complex; regulates nucleocytoplasmic transport

Expected phenotype

Knockouts lead to cardiovascular and renal defects

Human disease relevance

Associated with congenital anomalies involving the kidney and heart

Model applications

Used to study nuclear transport and developmental organogenesis

Keywords:

Nuclear pore, Transport, Kidney, Heart development

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Nup35

conditional Knockout mouse

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