Pawr conditional Knockout mouse

Target

Gene symbol :

Pawr

NCBI gene ID :

114774

Gene full name :

Prostate apoptosis response 4

Synonym :

Par-4

Protein function

Protein name :

Prostate apoptosis response protein 4

Pro-apoptotic protein; regulates NF-κB and tumor suppression pathways

Expected phenotype

Knockouts show resistance to apoptosis and altered tumor response

Human disease relevance

Linked to various cancers, neurodegeneration, and cardiac stress

Model applications

Studied in apoptosis, cancer resistance, and stress signaling

Keywords:

Apoptosis, Tumor suppressor, NF-κB, Stress response

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Pawr

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe