Target

Gene symbol :  
Pdia6
NCBI gene ID :  
71853
Gene full name :  
Protein disulfide isomerase family A, member 6
Synonym :  
TXNDC7

Protein function

Protein name :  
Protein disulfide-isomerase A6
ER chaperone protein that catalyzes disulfide bond formation and isomerization

Expected phenotype

Knockout impairs protein folding and stress responses; embryonic lethality

Human disease relevance

Associated with ER stress, diabetes, and cancer

Model applications

Used in ER stress response, protein folding, and redox biology studies

Keywords:

Protein folding, ER stress, Disulfide bonds, Chaperone

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Pdia6

conditional Knockout mouse

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