Pink1 conditional Knockout mouse

Target

Gene symbol :

Pink1

NCBI gene ID :

68943

Gene full name :

PTEN induced kinase 1

Synonym :

Park6

Protein function

Protein name :

Serine/threonine-protein kinase PINK1

Mitochondrial kinase involved in quality control; triggers mitophagy upon stress

Expected phenotype

Mitochondrial defects, motor deficits, altered dopamine levels

Human disease relevance

Associated with autosomal recessive Parkinson's disease

Model applications

Used in Parkinson’s research and mitochondrial quality control studies

Keywords:

Parkinson's, Mitochondria, Mitophagy, Neurodegeneration

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Pink1

conditional Knockout mouse

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