Pmel conditional Knockout mouse

Target

Gene symbol :

Pmel

NCBI gene ID :

20431

Gene full name :

Premelanosome protein

Synonym :

SILV, gp100, ME20

Protein function

Protein name :

PMEL

Structural component in melanosome formation, organizes fibrils for melanin synthesis

Expected phenotype

Pigmentation defects, hair graying

Human disease relevance

Implicated in ocular melanoma

Model applications

Pigmentation and melanoma research

Keywords:

Melanosome, Pigmentation, Melanoma

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Pmel

conditional Knockout mouse

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