Prps1 conditional Knockout mouse

Target

Gene symbol :

Prps1

NCBI gene ID :

19139

Gene full name :

Phosphoribosyl pyrophosphate synthetase 1

Synonym :

DFNX1, ARTS, Prs1

Protein function

Protein name :

PRPS1

Catalyzes synthesis of PRPP in purine/nucleotide biosynthesis

Expected phenotype

Altered purine metabolism, neurological defects

Human disease relevance

Linked to Arts syndrome, gout, Charcot–Marie–Tooth, deafness

Model applications

Models for metabolic and neuropathic disorders

Keywords:

Purine metabolism, Enzyme, Neuropathy

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Prps1

conditional Knockout mouse

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