Ptk7 conditional Knockout mouse

Target

Gene symbol :

Ptk7

NCBI gene ID :

71461

Gene full name :

Protein tyrosine kinase 7

Synonym :

Cck4

Protein function

Protein name :

Inactive tyrosine-protein kinase 7

Atypical receptor tyrosine kinase involved in Wnt signaling and planar cell polarity

Expected phenotype

Knockout mice show neural tube defects and abnormal development

Human disease relevance

Associated with congenital scoliosis and neural tube defects

Model applications

Used in developmental biology and Wnt/PCP pathway studies

Keywords:

Wnt signaling, Planar polarity, Development, Neural tube

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Ptk7

conditional Knockout mouse

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